FP koodi tarkoittaa XBB.1.4.1 linjaa.
Sublineage of: FP.1
Earliest sequence: 2023/04/05 (Singapore)
Most recent sequence: 2023/05/03 (Singapore)
Countries circulating: Singapore, 16 local cases and 2 cases with recent travel history from Malaysia (could be local as well)
Mutations on top of FP.1: T27134C > A28858C (N:R195S) > C9487T, A27917T (ORF8:8C)
A27917T changes the ORF8:8 stop codon (TGA) to a Cysteine (TGT), thus functionally restores the truncated ORF8. It'll be interesting to monitor if this restoration of ORF8 will confer any growth (dis)advantage over stock FP.1.
GISAID query: del21767, A27917T, A28858C
FP.1 has 69/70del
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